Tennessee vs. South Carolina odds, line: 2022 college football picks, week 12 predictions from proven model

The No. 5 Tennessee Vols will look to stay in the national title hunt when they take on the South Carolina Gamecocks on Saturday night. Tennessee bounced back from their loss to Georgia with a 66-24 win over Missouri last week. South Carolina earned its bowl eligibility by beating Vanderbilt before losing away to Florida.

Kickoff is scheduled for 7 p.m. ET. The Volunteers are favored at 22 points in the latest South Carolina vs. Tennessee odds from Caesars Sportsbook, while the over/under is set at 66. Before you jump into Tennessee vs. South Carolina tips, check out college football predictions from the model at SportsLine.

The SportsLine projection model simulates every FBS college football game 10,000 times. For the last 6+ years, the proprietary computer model has generated a staggering nearly $3,000 in profits for $100 players using its top-flight college football picks against the spread. Everyone who has followed it has seen huge returns.

Now the model has South Carolina in her sights against Tennessee. You can go to SportsLine to see the selection. Here are several college football odds for Tennessee vs. South Carolina:

  • Spread between Tennessee and South Carolina: Tennessee -22
  • Tennessee vs. South Carolina over/under: 66 points
  • Money line between Tennessee and South Carolina: South Carolina +1050, Tennessee -2000
  • Tennessee vs. South Carolina selection: See selection here

Featured Game | South Carolina Gamecocks vs. Tennessee Volunteers

Why South Carolina can cover

South Carolina has struggled with intermittent disagreements this season, but it has won five of its last seven games. The Gamecocks recorded back-to-back victories over then-No. 13 Kentucky and Texas A&M to allow them to compete against high-profile opponents. They were without leading rusher MarShawn Lloyd in the last two games due to a thigh contusion and he was ruled out for that game as well.

Quarterback Spencer Rattler has threw for 1,982 yards and eight touchdowns and hit junior wide receiver Antwane Wells Jr. 43 times for 590 yards and four points. South Carolina is 8-3 in their last 11 home games, so this isn’t an easy place for opposing teams.

Why Tennessee can cover

Tennessee is just one spot away from placing in the college football playoffs, so it’s highly motivated to win by margin. The Vols did just that last week, scoring multiple touchdowns late in the game in a 66-24 win over Missouri. They set a school record with 724 total rushing yards and surpassed 50 points in a game for the fifth time this season.

Quarterback Hendon Hooker added to his Heisman Trophy resume by throwing for 355 yards and three touchdowns while also rushing for 50 yards and a score. He leads an offense that ranks first nationwide in scoring (47.4 points per game) and overall offense (543.7). The Vols have covered the spread in eight of their ten games this season, making them one of the most profitable teams in the country.

How to make South Carolina vs. Tennessee picks

The model ran Tennessee vs. South Carolina 10,000 times and the results are in. The model is sloping down and it also generated a point spread pick that hits in well over 50% of the simulations. You can only see the selection at SportsLine.

So who will win South Carolina against Tennessee? And which side of the spread applies in well over 50% of the simulations? Visit SportsLine now to see which side of the Tennessee vs. South Carolina span you need to jump to on Saturday, all from the model who smashed his college football picks and find out.